Panadrex Max Tablet 48 Pcs

Panadrex Max Tablets

Active ingredients: Each tablet contains:
Paracetamol 500 mg
Caffeine anhydrous 65 mg.  

Mode of Action:
Panadrex Max contains Paracetamol which belongs to a group of medicines called analgesics and antipyretics.

Indications:
The tablets are recommended for the treatment of most painful and febrile conditions, for example, headaches, including migraine, backache, toothache, rheumatic pain and dysmenorrhea, and the relief of the symptoms of colds, influenza and sore throat.

Posology:
Adults and children ≥ 16 years: 2 tablets every 4-6 hours (Do not exceed 8 tablets in 24 hours)
Children 12-15 years: 1 tablet every 4-6 hours (Do not exceed 4 tablets in 24 hours)

Precautions:
• Do not exceed the stated dose.
• Do not take more frequently than every 4 hours.
• Paracetamol overdose may cause liver failure. 
• Used with caution in patients with renal or hepatic impairment, alcoholic liver disease, and glutathione depleted states.

Contraindications:
• Hypersensitivity to the active substances (paracetamol, caffeine) or any of the other excipients.
• Do not use with any other paracetamol-containing products. 
• Pregnancy and breastfeeding
• Not recommended for children under 12 years. 
• Concomitant use with caffein is not recommended.

Undesirable effects:
Adverse reactions identified during post-marketing use are reported voluntarily from a population of uncertain size, the frequency of these reactions is unknown but likely to be very rare (<1/10,000). When the recommended paracetamol-caffeine dosing regimen is combined with dietary caffeine intake, the resulting higher dose of caffeine may increase the potential for caffeine-related adverse effects.

Pharmacokinetic properties:
• Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract. It is relatively uniformly distributed throughout most body fluids and exhibits variable protein binding. Excretion is almost exclusively renal, in the form of conjugated metabolites. 
• Caffeine is absorbed readily after oral administration. Maximal plasma concentrations are achieved within one hour and the plasma half-life is about 3.5 hours. 65 - 80% of administered caffeine is excreted in the urine as 1-methyluric acid and 1-methylxanthine.    

Storage:
• Keep in a safe place, out of the reach and sight of children. 
• Store below 30°C.
 

How to use? 

Adults and children ≥ 16 years: 2 tablets every 4-6 hours (Do not exceed 8 tablets in 24 hours)
Children 12-15 years: 1 tablet every 4-6 hours (Do not exceed 4 tablets in 24 hours)

Ingredients

Paracetamol 500 mg
Caffeine anhydrous 65 mg.